What is Zaroxolyn (Metolaone)?

Zaroxolyn (also know by the generic name Metolazone) is a medication that is used to treat high blood pressure. It belongs to a group of medicines called diuretics. This type of medicine works with your kidneys to limit the amount of salt that is in your body. Too much salt in the body can lead to swelling of the blood vessels and make it more difficult for the heart to pump blood. Zaroxolyn (Metolazone) prevents the body from absorbing too much salt, thereby preventing the blood vessels from swelling which leads to a decrease in blood pressure and make it easier for the heart to pump blood.

Zaroxolyn (Metolazone) is also sometimes used to treat patients who have water retention due to congestive heart failure and to treat a particular kind of kidney disease called nephrotic syndrome. It removes excess water from the body in these conditions, allowing the patient to feel better in terms of breathing and urination.

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What are the side effects of Zaroxolyn (Metolazone)?

Side effects associated with the use of Zaroxolyn (Metolazone) may include headache, dizziness, muscle soreness, and blurred vision.

More severe side effects are possible and may include extreme thirst, fatigue, weakness, chest pain or heaviness which may radiate to the limbs, sweating, severe nausea, vomiting, stomach pain, changes in urination, numbness or tingling anywhere in the body, and a feeling of general illness. Stop using this medicine and contact your doctor immediately if you experience these or any other unusual symptoms while using Zaroxolyn (Metolazone).

Allergic reactions are possible when using this drug. Symptoms of an allergic reaction include a sudden rash, itchiness or swelling in the skin, mouth, or throat, and difficulty breathing. Seek emergency medical care if you believe you are having an allergic reaction to Zaroxolyn (Metolazone).

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What precautions are advised when using Zaroxolyn (Metolazone)?

Certain medicines may interact with how Zaroxolyn (Metolazone) works in your body. These may include medicines for diabetes, blood thinners, corticosteroids, non-steroidal anti-inflammatory drugs, other medicines for treating high blood pressure or other heart abnormalities, other medicines for water retention, as well as any herbal or nutritional supplements you may be taking.

Women who are pregnant, nursing, or plan on becoming pregnant should not use Zaroxolyn (Metolazone) unless specifically prescribed by their doctor.

What happens with an overdose of Zaroxolyn (Metolazone)?

Overdose symptoms of Zaroxolyn (Metolazone) may include weakness, nausea, dizziness, feeling like you might pass out, dry mouth, thirst, joint or muscle pain, as well as any of the side effects listed previously. Contact your doctor right away if you feel you have taken too much of this drug.

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